lit-0339
Fracture risk among patients with urolithiasis: a population-based cohort study
Melton LJ 3rd, Crowson CS, Khosla S, Wilson DM, O'Fallon WM (1998). Kidney International.
Study design and applicability are separate. A rigorous design in an unmatched population is not “strong evidence” for this record.
Status: Bibliographic identity verified (identifier match only). Identifier resolution proves bibliographic identity only; it does not prove that the card summary supports any medical claim, and it is not clinician review. Semantic verification count remains 0 for the catalog.
Filed in v0.4.0. Population cohort reporting that excess fracture risk in stone disease was confined to the spine, with no increase at hip, pelvis, humerus or forearm. Cited as a limit on how much a stone-and-calcium mechanism can explain when low readings appear at several sites at once. Applicability here is weak in a specific and stated way - this is a cohort of symptomatic stone formers, and the documented history is a single stone in one episode, so the comparison is to the mildest end of that cohort. Do not read it as evidence that stones are harmless to bone; the vertebral signal it reports is real.
Record overlap notes (research). one lifetime stone documented; low BMD at spine, hip and forearm
DOI: 10.1046/j.1523-1755.1998.00779.x · PMID: 9461107 · PMCID: —
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What cites this on the site
- Hypothesis H3 (contradicting)