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analysis version v0.4.1evidence current through 2026-08-10as of 2026-08-11last reviewed 2026-08-11review status: publishedsite mode: publicationpatient approval: obtainedclinician review: not performedindexing: enabled
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Literature card · launch set

lit-0235

European academy of andrology guidelines on Klinefelter Syndrome

Zitzmann M, Aksglaede L, Corona G, Isidori AM, Juul A, T'Sjoen G, Kliesch S, D'Hauwers K, Toppari J, Słowikowska-Hilczer J, Tüttelmann F, Ferlin A (2021). Andrology.

study design: guidelineaccess: abstract-onlylicense: all-rights-reservedrelevance: highBibliographic identity verified (identifier match only)

Study design and applicability are separate. A rigorous design in an unmatched population is not “strong evidence” for this record.

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Status: Bibliographic identity verified (identifier match only). Identifier resolution proves bibliographic identity only; it does not prove that the card summary supports any medical claim, and it is not clinician review. Semantic verification count remains 0 for the catalog.

Applicability / quality notes

European Academy of Andrology (endorsed by ESE) practice guideline: explicit karyotype indications, TRT principles, fertility, and comorbidity management for KS.

Record overlap notes (research). historical total T ~34 ng/dL; idiopathic hypogonadism; community XXY hypothesis; markedly low BMD for age

DOI: 10.1111/andr.12909 · PMID: 32959490 · PMCID: —

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