lit-0152
Urine calcium excretion predicts bone loss in idiopathic hypercalciuria
Asplin JR, Donahue S, Kinder J, Coe FL (2006). Kidney International.
Study design and applicability are separate. A rigorous design in an unmatched population is not “strong evidence” for this record.
Status: Bibliographic identity verified (identifier match only). Identifier resolution proves bibliographic identity only; it does not prove that the card summary supports any medical claim, and it is not clinician review. Semantic verification count remains 0 for the catalog.
Longitudinal BMD data in IH stone formers; links magnitude of calciuria to femoral-neck rate of loss. Cited IH literature describes mild BMD reduction / rate-of-loss association; does not account for spine T −4.3 magnitude. The record documents one lifetime stone, passed spontaneously, and no stones on CT urogram 2026-02-27, so this cohort applies weakly rather than not at all (COR-0042).
Record overlap notes (research). elevated 24h urine calcium values (not uniformly above male 300 (mg per day unit) threshold across serial collections); ongoing bone loss research framing; IH literature describes mild BMD reduction / rate-of-loss association, not spine T −4.3 magnitude; one lifetime stone, passed spontaneously; no stones on CT urogram 2026-02-27 — a stone-forming history at its mildest end, not an absence of one
DOI: 10.1038/sj.ki.5001778 · PMID: 16941029 · PMCID: —
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