lit-0049
Characterization of human immunoglobulin (Ig) isotype and IgG subclass response to Bartonella henselae infection
McGill SL, Regnery RL, Karem KL (1998). Infection and Immunity.
Study design and applicability are separate. A rigorous design in an unmatched population is not “strong evidence” for this record.
Status: Bibliographic identity verified (identifier match only). Identifier resolution proves bibliographic identity only; it does not prove that the card summary supports any medical claim, and it is not clinician review. Semantic verification count remains 0 for the catalog.
Western blot characterization of isotype/subclass responses in serologically confirmed CSD sera. Directly addresses IgG subclass—critical for patient’s IgG4↑/IgG1↓ hypothesis. Shows dominant IgG1 antigen recognition in CSD, not IgG4-driven pattern.
Record overlap notes (research). IgG4 high / IgG1 low laboratory pattern; question of infection-driven Ig subclass skew
DOI: 10.1128/IAI.66.12.5915-5920.1998 · PMID: 9826373 · PMCID: PMC108749
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What cites this on the site
- Hypothesis H4 (contradicting)