lit-0014
Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide
Adams JS, Song CF, Kantorovich V (1999). Annals of Internal Medicine.
Study design and applicability are separate. A rigorous design in an unmatched population is not “strong evidence” for this record.
Status: Bibliographic identity verified (identifier match only). Identifier resolution proves bibliographic identity only; it does not prove that the card summary supports any medical claim, and it is not clinician review. Semantic verification count remains 0 for the catalog.
Uncontrolled case series, n=5, ages 42–66; no control group; no fracture outcomes; the patient is younger than every enrolled subject. Source conclusion is associational ("was associated with" BMD increase), not causal proof. Not a treatment recommendation.
Record overlap notes (research). elevated 24h urine calcium values; markedly low BMD for age (~38); male low-BMD research phenotype
DOI: 10.7326/0003-4819-130-8-199904200-00012 · PMID: 10215562 · PMCID: —
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- Hypothesis H3 (supporting)